Guillermo Mazzolini Selected Research

Hymecromone

1/2022	Glycosylated 4-methylumbelliferone as a targeted therapy for hepatocellular carcinoma.
12/2018	4Mu Decreases CD47 Expression on Hepatic Cancer Stem Cells and Primes a Potent Antitumor T Cell Response Induced by Interleukin-12.
9/2015	Tumor Microenvironment Remodeling by 4-Methylumbelliferone Boosts the Antitumor Effect of Combined Immunotherapy in Murine Colorectal Carcinoma.
8/2015	4-methylumbelliferone inhibits hepatocellular carcinoma growth by decreasing IL-6 production and angiogenesis.
3/2012	Antitumor effects of hyaluronic acid inhibitor 4-methylumbelliferone in an orthotopic hepatocellular carcinoma model in mice.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Guillermo Mazzolini Research Topics

Disease

43	Neoplasms (Cancer) 01/2022 - 01/2002
10	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 01/2004
10	Liver Cirrhosis (Hepatic Cirrhosis) 05/2021 - 09/2008
10	Colorectal Neoplasms (Colorectal Cancer) 01/2018 - 08/2005
10	Carcinoma (Carcinomatosis) 09/2015 - 06/2002
8	Fibrosis (Cirrhosis) 05/2021 - 09/2008
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021 - 11/2014
2	Liver Neoplasms (Liver Cancer) 12/2018 - 11/2012
2	Obesity 12/2016 - 08/2015
2	Neoplasm Metastasis (Metastasis) 02/2013 - 11/2012
2	Pancreatic Neoplasms (Pancreatic Cancer) 08/2005 - 04/2004
1	Pain (Aches) 01/2022
1	Hyperalgesia 01/2022
1	Neuralgia (Stump Neuralgia) 01/2022
1	Peripheral Nerve Injuries 01/2022
1	Lung Neoplasms (Lung Cancer) 01/2021
1	Non-alcoholic Fatty Liver Disease 11/2020
1	Hepatitis B 09/2020
1	Hepatitis C 09/2020
1	Atrophy 02/2020
1	Alzheimer Disease (Alzheimer's Disease) 02/2020
1	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2020
1	Cognitive Dysfunction 02/2020
1	Wounds and Injuries (Trauma) 06/2019
1	Hyperprolactinemia 12/2016
1	Morbid Obesity 12/2016
1	Body Weight (Weight, Body) 12/2016
1	Glucose Intolerance 12/2016
1	Hyperinsulinism (Hyperinsulinemia) 12/2016
1	Fatty Liver 12/2016
1	Precancerous Conditions 08/2015
1	Melanoma (Melanoma, Malignant) 11/2014
1	Renal Cell Carcinoma (Grawitz Tumor) 11/2014
1	Stomach Neoplasms (Stomach Cancer) 02/2014
1	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 01/2014

Drug/Important Bio-Agent (IBA)

14	Interleukin-12 (IL 12)IBA 12/2018 - 03/2002
9	Monoclonal AntibodiesIBA 11/2014 - 01/2002
7	AntigensIBA 01/2014 - 06/2002
6	Thioacetamide (Thioacetamid)IBA 01/2020 - 09/2008
6	Hyaluronic Acid (Hyaluronan)IBA 12/2018 - 11/2009
5	HymecromoneIBA 01/2022 - 03/2012
5	Proteins (Proteins, Gene)FDA Link 09/2020 - 05/2009
5	Cyclophosphamide (Cytoxan)FDA LinkGeneric 09/2015 - 12/2009
4	Neoplasm Antigens (Tumor Antigens)IBA 01/2014 - 01/2002
4	CytokinesIBA 11/2012 - 01/2002
3	Insulin (Novolin)FDA Link 01/2020 - 03/2015
3	Therapeutic UsesIBA 01/2017 - 01/2015
3	ChemokinesIBA 11/2014 - 01/2003
3	Interleukin-8 (Interleukin 8)IBA 11/2014 - 08/2005
2	LipidsIBA 11/2020 - 12/2016
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020 - 03/2015
2	Insulin-Like Growth Factor I (IGF-1)IBA 01/2020 - 03/2015
2	Messenger RNA (mRNA)IBA 12/2018 - 08/2015
2	Biomarkers (Surrogate Marker)IBA 11/2014 - 02/2014
2	CollagenIBA 01/2013 - 09/2008
2	Conditioned Culture MediaIBA 09/2012 - 10/2011
2	Antineoplastic Agents (Antineoplastics)IBA 03/2012 - 11/2003
2	Biological ProductsIBA 04/2004 - 04/2004
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 09/2003 - 12/2002
1	Pharmaceutical PreparationsIBA 01/2022
1	OligodeoxyribonucleotidesIBA 01/2022
1	IMT504IBA 01/2022
1	Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA 05/2021
1	Nerve Growth Factor (NGF)IBA 05/2021
1	Polysaccharides (Glycans)IBA 05/2021
1	Guanidine (Guanidine Nitrate)FDA Link 01/2021
1	1D-142IBA 01/2021
1	GalactosamineIBA 06/2019
1	Concanavalin AIBA 06/2019
1	Epithelial Cell Adhesion MoleculeIBA 12/2018
1	Dopamine (Intropin)FDA LinkGeneric 12/2016
1	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 12/2016
1	Glucose (Dextrose)FDA LinkGeneric 12/2016
1	Transcription Factors (Transcription Factor)IBA 12/2016
1	ProlactinIBA 12/2016
1	Sterol Regulatory Element Binding Protein 1IBA 12/2016
1	Dihydrotachysterol (AT 10)IBA 12/2016
1	urelumabIBA 09/2015
1	NivolumabIBA 09/2015
1	Interleukin-6 (Interleukin 6)IBA 08/2015
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2015
1	Hypoxia-Inducible Factor 1IBA 01/2015
1	N 30IBA 11/2014
1	Vascular Endothelial Growth Factor CIBA 02/2014
1	Autocrine Motility Factor ReceptorsIBA 01/2014
1	Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA 01/2014
1	VaccinesIBA 01/2014
1	HLA Antigens (Human Leukocyte Antigens)IBA 01/2014
1	Viral VaccinesIBA 02/2013
1	Interleukin-15 (Interleukin 15)IBA 02/2013

Therapy/Procedure

13	Therapeutics 01/2022 - 01/2003
13	Immunotherapy 09/2015 - 01/2002
3	Ligation 06/2019 - 01/2013
3	Injections 08/2005 - 04/2004
2	Cell- and Tissue-Based Therapy (Cell Therapy) 02/2020 - 04/2004
2	Drug Therapy (Chemotherapy) 01/2015 - 11/2007
1	Intravenous Injections 02/2020
1	Immunomodulation 08/2015
1	Radiotherapy 01/2015
1	Molecular Targeted Therapy 01/2015